Table 2.

Correlation analysis of plasma galectin-3-binding protein (plasma/serum) and clinical/serological parameters with Spearman's rank correlation coefficients (r) and p values

	SLE-DK (plasma)			SLE-SE (plasma)			SLE-INF-α (serum)
	n	r	p Value	n	r	p Value	n	r	p Value
Age	70	−0.32	0.01	68	0.0018	0.99	26	−0.16	0.43
Nephritis*	70	0.14	0.24	68	0.049	0.69	26	0.42	0.03
SLEDAI*	70	0.41	0.0004	68	−0.0025	0.98	26	0.38	0.05
SLICC/ACR Damage Index	70	−0.08	0.53	68	0.036	0.77		N/A
Immunosuppressive treatment†	70	−0.05	0.68	68	0.052	0.68	26	0.29	0.16
ESR	66	0.57	<0.0001		N/A			N/A
Haemoglobin	70	−0.29	0.02	68	−0.21	0.08	26	0.17	0.41
Neutrophils	70	−0.36	0.002	67	0.037	0.77		N/A
Lymphocytes	70	−0.04	0.72	67	−0.084	0.50	26	0.11	0.58
Platelets	70	−0.02	0.85		N/A		26	−0.06	0.78
Anti-dsDNA	69	0.35	0.003	68	−0.094	0.45	26	0.54	0.005
Anti-Sm	69	0.26	0.03	68	0.0021	0.99		N/A
Anti-Ro	69	0.32	0.01		N/A			N/A
Anti-La	69	0.25	0.04		N/A			N/A
C3 low	69	−0.03	0.78	68	0.095	0.44	26	−0.30	0.14
C4 low	69	−0.09	0.45	68	0.14	0.26	26	−0.28	0.17

Bold denotes significant observations (p<0.05). *All of the clinical manifestations included in the SLEDAI were tested and no other significant correlations were detected.

†At inclusion. Immunosuppressive treatment included prednisolone, methotrexate, mycophenylate mofetil, azathioprine and plaquenil.

C3, complement component C3; C4, complement component C4; DK, Denmark; ESR, erythrocyte sedimentation rate; N/A, not available; IFN-α, interferon-α; SE, Sweden; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index; SLICC/ACR, Systemic Lupus International Collaborating Clinics/American College of Rheumatology.