Table II.
Univariate and multivariate logistic regression analysis of factors predicting progression or mortality in patients exhibiting endometrioid type endometrial cancer.
| Unadjusted | Adjusted | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Variable | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age at surgery, years | ||||||
| <62 | 1 | 1 | ||||
| ≥62 | 5.55 | 1.75–17.63 | 0.004 | 1.57 | 0.47–5.26 | 0.460 |
| Risk of recurrence | ||||||
| Low/Low-intermediate | 1 | 1 | ||||
| High/High-intermediate | 10.26 | 3.38–31.12 | <0.001 | 9.42 | 1.21–73.62 | 0.032 |
| Adjuvant therapy | ||||||
| No | 1 | 1 | ||||
| Yes | 3.74 | 1.20–11.61 | 0.023 | 0.96 | 0.13–6.97 | 0.970 |
| Histologic subtype | ||||||
| Endometrioid, pure | 1 | |||||
| Endometrioid, other | 1.67 | 0.57–4.94 | 0.350 | - | - | - |
| Tumor size, cm | ||||||
| <4 | 1 | |||||
| ≥4 | 2.05 | 0.68–6.22 | 0.200 | - | - | - |
| Peritoneal cytology | ||||||
| Negative | 1 | |||||
| Positive | 3.32 | 0.43–25.92 | 0.220 | - | - | - |
| Surgery | ||||||
| Laparoscopy | 1 | |||||
| Laparotomy | 2.50 | 0.72–8.66 | 0.150 | - | - | - |
| Lymph node dissection | ||||||
| Pelvic lymph node dissection | 1 | |||||
| Pelvic and para-aortic lymph node dissection | 2.21 | 0.73–6.73 | 0.150 | - | - | - |
| Pelvic lymph nodes removed, n | ||||||
| <25 | 1 | |||||
| ≥25 | 1.36 | 0.47–3.87 | 0.570 | - | - | - |
HR, hazard ratio; CI, confidence interval. Unadjusted and adjusted data, if any, were obtained by univariate and multivariate analyses, respectively.