Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Percentage of hemolysis and mortality related to null-loaded NPs, AMB in free and AMB-loaded NP forms.
Notes: (A) Hemolysis related to null-loaded NP, free AMB and AMB-loaded NP forms. Data were from three independent experiments. (B) Determination of LD50. The LD50 of null-loaded NPs, free AMB and AMB-loaded NPs was >1,000 mg/kg, 20 mg/kg, and 200 mg/kg, respectively, in healthy mice (n=10).
Abbreviations: AMB, amphotericin B; LD50, lethal dose for 50% of animals; NP, nanoparticle.
