Table I.
Clinicopathological parameters and MGMT methylation status of tissue samples from laryngeal squamous cell carcinoma patients.
| Variable | Patients, n | MGMT methylation status, n (%) | P-value | |
|---|---|---|---|---|
|
| ||||
| M | U | |||
| Gender | 0.517 | |||
| Male | 44 | 23 (52.3) | 21 (47.7) | |
| Female | 6 | 4 (66.7) | 2 (33.3) | |
| Age, years | 0.162 | |||
| <60 | 24 | 16 (66.7) | 8 (33.3) | |
| ≥60 | 26 | 11 (42.3) | 15 (57.7) | |
| Tumor T stage | 0.982 | |||
| T1 + T2 | 24 | 13 (54.2) | 11 (45.8) | |
| T3 + T4 | 26 | 14 (53.8) | 12 (46.2) | |
| Lymphatic metastasis | 0.968 | |||
| Positive | 11 | 6 (54.5) | 5 (45.5) | |
| Negative | 39 | 21 (53.8) | 18 (46.2) | |
| Tumor Grade | 0.586 | |||
| Well-differentiated | 29 | 18 (62.0) | 11(38.0) | |
| Moderately and poorly differentiated | 21 | 9 (42.9) | 12 (57.1) | |
| Type | 0.747 | |||
| Glottic | 23 | 13 (56.5) | 10 (43.5) | |
| Supraglottic | 27 | 14 (51.9) | 13 (47.1) | |
P<0.05 was considered to indicate a statistically significant difference. The χ2 test was used to analyze the data. MGMT, O6-methylguanine-DNA methyltransferase; M, methylated and partially methylated; U, unmethylated.