Table I.
Comparison of clinical data between the clopidogrel resistant and sensitive groups.
| Clopidogrel | |||||
|---|---|---|---|---|---|
|
|
|||||
| Variable | Class | Sensitive (n=252) | Resistant (n=51) | Statisticsa | P-value |
| Gender | Female | 72 (77.42) | 21 (22.58) | 3.168 | 0.075 |
| Male | 180 (85.71) | 30 (14.29) | |||
| Hypertension | No | 72 (92.31) | 6 (7.69) | 6.268 | 0.012 |
| Yes | 180 (80.00) | 45 (20.00) | |||
| Coronary heart disease | No | 192 (85.33) | 33 (14.67) | 2.927 | 0.087 |
| Yes | 60 (76.92) | 18 (23.08) | |||
| Diabetes | No | 237 (87.78) | 33 (12.22) | 37.628 | <0.001 |
| Yes | 15 (45.45) | 18 (54.55) | |||
| Smoking | No | 153 (80.95) | 36 (19.05) | 1.762 | 0.184 |
| Yes | 99 (86.84) | 15 (13.16) | |||
| Drinking | No | 198 (84.62) | 36 (15.38) | 1.537 | 0.215 |
| Yes | 54 (78.26) | 15 (21.74) | |||
| CCB | No | 165 (88.71) | 21 (11.29) | 10.566 | 0.001 |
| Yes | 87 (74.36) | 30 (25.64) | |||
| ACEI | No | 216 (84.71) | 39 (15.29) | 2.718 | 0.099 |
| Yes | 36 (75.00) | 12 (25.00) | |||
| β-blocker | No | 237 (85.87) | 39 (14.13) | 14.052 | <0.001 |
| Yes | 15 (55.56) | 12 (44.44) | |||
| Statin | No | 15 (100.00) | 0 (0.00) | 2.054 | 0.152 |
| Yes | 237 (82.29) | 51 (17.71) | |||
| Proton pump inhibitor | No | 234 (85.71) | 39 (14.29) | 12.767 | <0.001 |
| Yes | 18 (60.00) | 12 (40.00) | |||
| Age (years) | 63 (56.5,71) | 67 (62,69) | 1.941 | 0.052 | |
| BUN (mmol/l) | 5.03 (4.05,6.23) | 4.2 (3.85,5.82) | −1.561 | 0.119 | |
| Cr (umol/l) | 72.95 (59.15,88.1) | 79.1 (60.9,111.5) | 2.286 | 0.022 | |
| UA (umol/l) | 319.9 (255.15,391.85) | 367.3 (273.5,429.1) | 1.845 | 0.065 | |
| FBG (mmol/l) | 5.57 (5.11,6.57) | 6.11 (5.49,8.02) | 3.375 | 0.001 | |
| HCY (umol/l) | 15.92 (13.44,21.28) | 19.46 (15.46,22.65) | 2.31 | 0.021 | |
| hs-CRP (mg/l) | 0.95 (0.5,2.65) | 4.21 (2.21,11.97) | 6.582 | <0.001 | |
| Cholesterol (mmol/l) | 4.72 (3.87,5.59) | 4.96 (3.82,5.34) | −0.449 | 0.654 | |
| Triglycerides (mmol/l) | 1.31 (0.95,2.05) | 1.39 (1.23,2.83) | 2.35 | 0.019 | |
| HDL (mmol/l) | 1.04 (0.91,1.25) | 1.08 (0.89,1.34) | 0.614 | 0.539 | |
| LDL (mmol/l) | 2.68 (1.98,3.39) | 2.7 (2,2.92) | −1.679 | 0.093 | |
| Platelet count (×109) | 157.5 (135.15,193.7) | 173 (127,206.3) | 0.299 | 0.765 | |
CCB, calcium channel blocker; ACEI, angiotensin-converting enzyme inhibitor; BUN, blood urea nitrogen; Cr, creatinine; UA, uric acid; FBG, fasting blood glucose; HCY, homocysteine; hs-CRP, high-sensitivity C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
a
Some of the statistics are χ2 values and some are Z values.