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Th1/Th2 and Tc1/Tc2 ratio imbalance in patients with ankylosing spondylitis. The percentages of (A) Th1 and (B) Th2 cells, (C) Th1/Th2 ratio, percentages of (D) Tc1 and (E) Tc2 cells and (F) Tc1/Tc2 ratio are shown for the control, mild ankylosing spondylitis and severe ankylosing spondylitis groups. Different letters indicate a significant difference among the groups (P<0.05). Th, T helper; Tc, T cytotoxic.
