Table 5.
Heritabiilty of Subcortical Shape in Multiplex-Multigenerational Families with Schizophrenia.
| Region | Hemisphere | Heritability |
% surface heritable |
|---|---|---|---|
| Accumbens | L | 0.48(0.27–0.75) | 61 |
| R | 0.44(0.31–0.75) | 12 | |
| Amygdala | L | 0.48(0.38–0.59) | 11 |
| R | 0.62(0.52–0.76) | 3 | |
| Caudate | L | 0.45(0.21–1.00) | 78 |
| R | 0.43(0.20–0.80) | 61 | |
| Hippocampus | L | 0.49(0.28–0.72) | 28 |
| R | 0.42(0.22–0.82) | 64 | |
| Pallidum | L | 0.46(0.35–0.66) | 10 |
| R | n.s. | n.s. | |
| Putamen | L | 0.47(0.20–1.00) | 83 |
| R | 0.49(0.20–1.00) | 82 | |
| Thalamus | L | 0.41(0.21–0.69) | 76 |
| R | 0.48(0.21–0.70) | 97 |
All results are False Discovery Rate (FDR) corrected and thresholded at p<0.05. Heritability = mean(minimum-maximum) heritability in the thresholded surfaces after controlling for age and site; % Surface = the percent of the subcortical surface that has significant heritability; ROI = Region Of Interest; n.s.= not significant.