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MTR-induced repression of H3K18 acetylation in HeLa cells as monitored by confocal microscopy. (A) Representative population of untreated and 10 μM MTR-treated HeLa cells for 9 h. The scale bar is 10 μM. (B) Quantification of the extent of repression of H3K18 acetylation upon increasing concentrations of MTR treatment (0.1–10 μM), using Image J software. Statistical analyses were performed over 300 cells in each case.
