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Engineering Dicer expression in CHO DUKXB-11 cells affects growth behavior. (a) Overexpression of Dicer in three stable bulk cell lines compared to DUKXB-11 host cells was analyzed on day 2 during three individual batch cultivations by qPCR (n = 3, Actb used as reference gene, error bars represent s.d. of mean). (b) Three independent batch cultivations of all cell lines were performed. Viable cell densities (VCD) and viability were analyzed every 24 h.
