Table 8.
Skin model | Type | Company | Cell origin | Reference |
---|---|---|---|---|
EpiDerm™ (EPI-200) | Epidermal | MatTek, MA, USA | Male foreskin | Hayden et al. (2006) |
EpiDermFT™ (EFT) | Full thickness (collagen matrix) | MatTek, MA, USA | Male foreskin | Hayden et al. (2003) |
EST-1000 (EST) | Epidermal | Cell Systems, Troisdorf, Germany | Male foreskin | Hoffmann et al. (2005) |
AST-2000 (AST) | Full thickness (collagen matrix) | Cell Systems, Troisdorf, Germany | Male foreskin | Hoffmann et al. (2003) |
Episkin™ | Epidermal | SkinEthic™ laboratories, Nice, France | Adult breast skin |
Tinois et al. (1991) Netzlaff et al. (2005) |
Episkin™ FTM | Full thickness (polycarbonate and collagen matrix) | SkinEthic™ laboratories, | Adult breast skin | Eilstein et al. (2010) |
SkinEthik™ RHE | Epidermal | SkinEthic™ laboratories, Nice, France |
Adult abdomen Male foreskin |
Netzlaff et al. (2005) Eilstein et al. (2014) |
Phenion® FT (PFT) | Full thickness (collagen matrix) | Henkel, Düsseldorf, Germany | Male foreskin | Mewes et al. (2007) |
StrataTest® | Epidermal | StrataTech, MA, USA | NIKS® human keratinocyte cell line | Slavik et al. (2007) |
EuroSkin® | Epidermal | EuroDerm, Leipzig, Germany | Hair follicles | http://www.eurodermbiotech.de (2011) |
EPI-MODEL | Epidermal | LabCyte, Aichi, Japan | ? | Katoh et al. (2009) |
NIKS®, spontaneously immortalized near-diploid human keratinocyte cell line
aAdapted from: Jäckh et al. (2012)