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. Author manuscript; available in PMC: 2015 Nov 15.
Published in final edited form as: Cancer Res. 2014 Aug 29;74(22):6419–6429. doi: 10.1158/0008-5472.CAN-13-3212

Figure 4.

Figure 4

Increased angiogenic potential in SS.BN3 consomic rats. (A) Density of CD31+ blood vessels in matrigel plugs implanted in SS (n = 20) and SS.BN3 (n = 10) consomic rats. (B) Mean CD31+ blood vessel density in matrigel plugs implanted in SS and SS.BN3 consomic rats was calculated from the entire matrigel plug cross-section. Data are presented as the mean vascular density per mm2 ± SEM. *P<0.05 as determined by Student unpaired t test. (C) Density of SH2B3+ blood vessels in DMBA-induced tumors of SS (n = 9) and SS.BN3 (n = 9) consomic rats. (D) Mean density of SH2B3+ blood vessels was calculated from 400X images of the entire tumor cross-section that were acquired using an automated microscope. Data are presented as the mean vascular density per area ± SEM. **P<0.01 as determined by Student unpaired t test.