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. 2014 Nov 20;13:443. doi: 10.1186/1475-2875-13-443

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© Valle and Tucker Lima; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Coldspots (CS) and hotspots (HS) reveal substantially different spatial patterns than Figure 4 . Upper and lower panels show results for P. vivax and P. falciparum, respectively. Persistent hotspots (red) are areas that were classified as hotspots throughout the five-year study period (2004-2008). Intermittent hotspots (light red) are areas that were classified at least once as a hotspot but not in all five years. Analogous definitions were used for persistent (blue) and intermittent (light blue) coldspots. Finally, potential hotspots are shown in grey. Letters indicate state names (AC = Acre, AM = Amazonas, RR = Roraima, AP = Amapa, PA = Para, and RO = Rondonia).