Table 4.
Laboratory data and outcomes of the elderly and younger patients with candidemia
| Characteristics | Elderly patients (≥65 years, n =63) | Younger patients (16–60 years, n =84) | p value |
|---|---|---|---|
| Laboratory data | |||
| Hemoglobin level (g/L) | 86.9 ± 29.1 | 94.2 ± 30.9 | 0.148 |
| Platelet count (×109/L) | 163.4 ± 93.7 | 153.6 ± 117.1 | 0.586 |
| Serum creatinine level ( mol/L) | 112.0 ± 95.3 | 82.4 ± 65.6 | 0.027 |
| Blood sugar level (mmol/L) | 9.3 ± 5.1 | 6.7 ± 2.8 | 0.001 |
| Serum sodium level (mmol/L) | 138.6 ± 5.8 | 137.5 ± 5.4 | 0.238 |
| Serum potassium level (mmol/L) | 3.9 ± 1.0 | 3.8 ± 0.9 | 0.526 |
| Total bilirubin level ( mol/L)b | 16.3 (6.2-31.8) | 13.9 (8.3-30.6) | 0.271 |
| High fever (>39°C)a | 19 (30.2) | 32 (38.1) | 0.317 |
| Removal of CVCa | 14/32 (43.8%) | 15/26 (57.7) | 0.291 |
| CVC-related candidemiaa | 8 (12.7%) | 10 (11.9%) | 0.885 |
| Concurrent bloodstream infectiona | 8 (12.7) | 14 (16.7) | 0.505 |
| APACHE II score | 20.3 ± 8.1 | 14.6 ± 7.3 | 0.001 |
| Age-adjusted APACHE II score | 16.2 ± 7.7 | 13.9 ± 7.1 | 0.063 |
| Septic shocka | 27 (42.9) | 24 (28.6) | 0.072 |
| 30-day mortality ratea | 20 (31.7) | 14 (16.7) | 0.032 |
Data are n (%), mean ± SD or median (IQR).
APACHE, Acute Physiology and Chronic Health Evaluation; CVC, central venous catheter.
aChi-square test; bMann-Whitney U test; Unspecified: Two-independent samples t-test.