Table 3.
Overall and age- and sex-specific incidence densities and relative hazard of gallstone in the osteoporosis and comparison cohorts
| Factor | Osteoporotic group | Comparative group | Crude HR | Adjust HR | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Incident cases | Person-years | ID 1 | 95% CI | Incident cases | Person-years | ID 1 | 95% CI | |||
| Age (y)a | ||||||||||
| 50-64 | 42 | 3080.05 | 13.64 | 9.54 - 17.73 | 103 | 12702.40 | 8.11 | 6.55 - 9.67 | 1.68 (1.17 - 2.40)** | 1.56 (1.06 - 2.28)* |
| 65-79 | 60 | 3846.65 | 15.60 | 11.68 - 19.51 | 170 | 15720.01 | 10.81 | 9.20 - 12.43 | 1.44 (1.07 - 1.94)* | 1.25 (0.92 - 1.71) |
| ≥ 80 | 12 | 868.91 | 13.81 | 6.05 - 21.57 | 38 | 3544.48 | 10.72 | 7.33 - 14.11 | 1.28 (0.67 - 2.46) | 1.31 (0.64 - 2.68) |
| Sexb | ||||||||||
| Men | 17 | 1142.92 | 14.87 | 7.86 - 21.89 | 48 | 4719.56 | 10.17 | 7.31 - 13.03 | 1.46 (0.84 - 2.54) | 1.09 (0.60 - 1.96) |
| Women | 97 | 6652.69 | 14.58 | 11.70 - 17.46 | 263 | 27247.33 | 9.65 | 8.49 - 10.81 | 1.51 (1.20 - 1.91)** | 1.40 (1.09 - 1.79)** |
| Total | 114 | 7795.61 | 14.62 | 11.96 - 17.29 | 311 | 31966.89 | 9.73 | 8.65 - 10.80 | 1.50 (1.21 - 1.86)*** | 1.35 (1.07 - 1.69)* |
*p <0.05,**p <0.01, ***p <0.001.
HR, hazard ratio; ID, incidence density (per 1000 patient-years); CI, confidence interval.
1Based on the Poisson assumption.
aAdjusted for sex, age, monthly income, region, urbanization level, hypertension, hyperlipidemia, diabetes, cirrhosis, spinal cord injury, hormone replacement, and clofibrate.
bAdjusted for age, monthly income, region, urbanization level, hypertension, hyperlipidemia, diabetes, cirrhosis, spinal cord injury, hormone replacement, and clofibrate.