Table 2.
Mean (SD) of groups, mean (SD) difference within groups, mean (95% CI) difference between groups for exercise capacity immediately following intervention
| Group | Difference within group | Difference between groups | ||||||
|---|---|---|---|---|---|---|---|---|
| Week 0 | Week 8 | Week 8 minus week 0 | Week 8 minus week 0 | ANCOVA | ||||
| Mean (SD) | Mean (SD) | Mean (SD) | Mean difference (95% CI) | p Value | ||||
| 6MWT | EG | CG | EG | CG | EG | CG | ||
| n = 18 | n = 17 | n = 17 | n = 17 | n = 17 | n = 17 | |||
| 6MWD, m | 475 (79) | 469 (81) | 548 (72) | 489 (83) | 73 (29) | 20 (32) | 53 (32 to 74) | <0.0001* |
| ICT | EG | CG | EG | CG | EG | CG | ||
| n = 18 | n = 17 | n = 16 | n = 17 | n = 16 | n = 17 | |||
| Peak work rate, W | 108 (41) | 110 (33) | 116 (43) | 107 (30) | 8 (7) | -4 (12) | 12 (5 to 19) | 0.002* |
| VO2peak, L/min | 1.6 (0.5) | 1.6 (0.4) | 1.6 (0.5) | 1.6 (0.4) | 0.1 (0.1) | 0.1 (0.3) | -0.01 (-0.16, 0.14) | 0.882 |
| VEpeak, L/min | 56 (21) | 55 (12) | 59 (24) | 55 (13) | 3 (7) | 0.3 (11) | 2.84 (-4.13, 9.80) | 0.412 |
| HR at peak work rate, bpm | 121 (22) | 123 (13) | 120 (23) | 126 (12) | -0.5 (8) | 3 (11) | -4 (-11, 3) | 0.238 |
| VE at isowork, L/min | 56 (21) | 52 (12) | 55 (24) | 53 (13) | -0.6 (5) | 1.3 (8) | -2 (-7, 3) | 0.411 |
| HR at isowork, bpm | 121 (22) | 119 (11) | 117 (21) | 122 (13) | -4 (9) | 3 (8) | -7 (-13, -0.3) | 0.040* |
| Borg dyspnoea at isowork | 4 (2) | 3(2) | 4(2) | 4(2) | 0 (2) | 1 (2) | -0.5 (-1.6, 0.6) | 0.366 |
| RPE at isowork | 4 (3) | 4 (2) | 4 (2) | 5 (2) | -0.4 (2) | 0.2 (2) | -0.5 (-1.6, 0.5) | 0.315 |
| ECT | EG | CG | EG | CG | EG | CG | ||
| n = 18 | n = 17 | n = 16 | n = 17 | n = 16 | n = 17 | |||
| Endurance cycle time, seconds | 319 (130) | 311 (80) | 534 (268) | 308 (113) | 216 (254) | -3 (113) | 222 (84, 360) | 0.003* |
| VE at isotime, L/min | 51 (15) | 53 (13) | 50 (15) | 52 (12) | -0.1 (5) | -1 (10) | 0.6 (-5, 6) | 0.824 |
| Borg dyspnoea at isotime | 5 (2) | 3 (2) | 3 (2) | 4 (2) | -1 (2) | 1 (2) | -1.2 (-2.3, -0.04) | 0.043* |
| Borg dyspnoea at test end | 5 (3) | 4 (2) | 5 (2) | 5 (2) | -0.2 (1) | 1 (2) | -1.1 (-2.3, 0.1) | 0.076 |
| RPE at isotime | 5 (3) | 5 (2) | 4 (3) | 5 (2) | -1 (2) | -0.3 (2) | -0.9 (-2.2, 0.3) | 0.148 |
SD = standard deviation; CI = confidence interval; ANCOVA = analysis of covariance; 6MWT = six minute walk test; EG = exercise training group; CG = control group; n = number; 6MWD = six minute walk distance; m = metre; ICT = incremental cycle test; W = watts; VO2peak = peak oxygen uptake; L/min = litres per minute; VEpeak = minute ventilation at peak work rate; HR = heart rate; bpm = beats per minute; VE = minute ventilation; RPE = rate of perceived exertion; ECT = endurance cycle test; *p <0.05.