Table 3.
Outcome | Week 8 minus week 0 | ANCOVA | Week 26 minus week 0 | ANCOVA |
---|---|---|---|---|
Mean difference | p Value | Mean difference | p Value | |
(95% CI) | (95% CI) | |||
Exercise capacity | n = 34 | n = 31 | ||
6MWD, m | 53 (32, 74) | <0.001* | 45 (17, 73) | 0.003* |
HRQoL | n = 34 | n = 33 | ||
SGRQ Total | -7 (-13, -1) | 0.033* | -4 (-12, 4) | 0.293 |
SGRQ Symptoms | -15 (-27, -2) | 0.021* | -4 (-18, 9) | 0.530 |
SGRQ Activity | -5 (-13, 3) | 0.209 | -4 (-15, 8) | 0.505 |
SGRQ Impacts | -5 (-12, 2) | 0.183 | -4 (-12, 5) | 0.383 |
CRQ Total | 6.4 (2.1, 10.7) | 0.005* | 13.1 (5.2 to 20.9) | 0.002* |
CRQ Dyspnoea | 2.2 (0.6, 3.7) | 0.007* | 3.4 (1.5, 5.4) | 0.001* |
CRQ Fatigue | 1.3 (-0.02, 2.6) | 0.053 | 2.9 (0.6, 5.2) | 0.015* |
CRQ Emotional Function | 2.4 (0.7, 4.2) | 0.008* | 5.5 (2.0, 8.9) | 0.003* |
CRQ Mastery | 1.4 (0.1, 2.7) | 0.036* | 2.7 (1.0, 4.3) | 0.002* |
Physical activity | n = 31 | n = 30 | ||
Average daily steps | 1514 (15, 3012) | 0.048* | 1206 (-156, 2568) | 0.08 |
Average daily EE, cal | 86 (-57, 230) | 0.227 | 158 (-8, 323) | 0.062 |
Average daily METs | 0.08 (0.01, 0.15) | 0.038* | 0.11 (0.03, 0.20) | 0.012* |
CI = confidence interval; ANCOVA = analysis of covariance; n = number; 6MWD = six-minute walk distance; m = metre; HRQoL = health-related quality of life; SGRQ = St George’s Respiratory Questionnaire; CRQ = Chronic Respiratory Disease Questionnaire; EE = energy expenditure; cal = calorie; MET = metabolic equivalent.
*p <0.05.