Table 2.

List of oppositely up- or downregulated KEGG pathways in the longissimus dorsi muscle tissue compared to intramuscular, subcutaneous, and omental adipose tissues in Hanwoo.

	KEGG ID	Pathway	Fold enrichment	Bonferroni
Upregulated	bta05012	Parkinson's disease†	4.2	1.4E − 27
	bta05010	Alzheimer's disease†	3.7	5.3E − 26
	bta00190	Oxidative phosphorylation†	4.0	8.3E − 26
	bta05016	Huntington's disease†	3.4	2.2E − 22
	bta03050	Proteasome†	5.3	9.5E − 15
	bta04260	Cardiac muscle contraction	3.7	3.2E − 10
	bta00020	Citrate cycle (TCA cycle)†	5.1	8.7E − 09
	bta05410	Hypertrophic cardiomyopathy (HCM)	2.7	4.9E − 04
	bta05414	Dilated cardiomyopathy	2.5	1.9E − 03
	bta00230	Purine metabolism	2.0	2.8E − 03
	bta04120	Ubiquitin mediated proteolysis	2.1	3.2E − 03
	bta00620	Pyruvate metabolism†	3.0	2.7E − 02
	bta00010	Glycolysis/gluconeogenesis	2.6	2.9E − 02
Downregulated	bta04510	Focal adhesion‡	1.9	1.3E − 06
	bta04512	ECM-receptor interaction‡	2.4	5.0E − 06
	bta04640	Hematopoietic cell lineage	2.3	1.9E − 05
	bta04062	Chemokine signaling pathway‡	1.8	4.7E − 05
	bta04360	Axon guidance‡	2.0	7.5E − 05
	bta04670	Leukocyte transendothelial migration	2.0	1.1E − 04
	bta04060	Cytokine-cytokine receptor interaction	1.7	6.3E − 04
	bta00600	Sphingolipid metabolism	2.7	3.7E − 03
	bta04514	Cell adhesion molecules (CAMs)	1.8	4.2E − 03
	bta04810	Regulation of actin cytoskeleton‡	1.6	5.9E − 03
	bta04142	Lysosome	1.8	6.6E − 03
	bta04666	Fc gamma R-mediated phagocytosis	2.0	8.6E − 03

^†Downregulated in the intramuscular adipose tissue.

^‡Upregulated in the intramuscular adipose tissue.