(a).
| Variable | Atorvastatin | Policosanol + atorvastatin |
P value |
|---|---|---|---|
| Number of patients | 12 | 14 | |
| Demographics | |||
| Age (years; mean ± SD) | 55.31 ± 6.72 | 54.73 ± 7.35 | >0.05 |
| Men [n (%)] | 6 (50.0) | 11 (78.6) | >0.05 |
| Body mass index (kg/m2; mean ± SD) | 25.73 ± 2.93 | 26.26 ± 3.40 | >0.05 |
| Clinical profile [n (%)] | |||
| Hypertension | 7 (58.3) | 8 (61.5) | >0.05 |
| Diabetes | 4 (33.3) | 6 (46.2) | >0.05 |
| Family history of coronary heart disease | 1 (8.3) | 2 (15.4) | >0.05 |
| Smoker | 6 (50.0) | 6 (46.2) | >0.05 |
| Laboratory values (mean ± SD) | |||
| White blood cell count (×109/L; mean ± SD) | 7.54 ± 1.66 | 6.15 ± 1.61 | 0.04 |
| Neutrophils (×109/L; mean ± SD) | 4.46 ± 1.05 | 3.30 ± 1.06 | 0.01 |
| Erythrocyte sedimentation rate (mm/h; mean ± SD) |
12.78 ± 13.09 | 9.86 ± 10.26 | >0.05 |
| high-sensitivity C-reactive protein [mg/L; median (P25, P75)] |
2.86 (1.18, 10.99) |
1.27 (0.90, 1.82) |
>0.05 |
| Alanine transaminase (U/L; mean ± SD) | 28.00 ± 12.10 | 28.71 ± 15.09 | >0.05 |
| Aspartate aminotransferase (U/L; mean ± SD) | 19.58 ± 7.86 | 21.29 ± 10.38 | >0.05 |
| Creatinine (μmol/L; mean ± SD) | 71.74 ± 14.64 | 75.20 ± 8.80 | >0.05 |
| Blood urea nitrogen (mmol/L; mean ± SD) | 5.68 ± 1.36 | 5.91 ± 1.47 | >0.05 |