Table 1.
Candidate genes involved in AMD pathogenesis, following GWAS.
| Gene | Locus | SNP |
|---|---|---|
| C2-CFB | 6p21.33 | rs429608 A/G |
| C3 | 19p13.3 | rs2230199 C/G |
| TIMP3 | 22q12.3 | rs5749482 C/G |
| APOE | 19q13.2 | rs4420638 G/A |
| CETP | 16q21 | rs1864163 G/A |
| VEGFA | 6p21.1 | rs943080 C/T |
| TNFRSF10A | 8p21.3 | rs13278062 G/T |
| LIPC | 15q21 | rs920915 C/G |
| CFI | 4q25 | rs4698775 G/T |
| COL10A1 | 6q21 | rs3812111 A/T |
| COL8A1 | 3q12.1 | rs13081855 G/T |
| IER3 | 6p21.3 | rs3130783 A/G |
| SLC16A8 | 22q13.1 | rs8135665 C/T |
| TGFBR1 | 9q22 | rs334353 T/G |
| RAD51B | 14q23 | rs8017304 A/G |
| ADAMTS9 | 3p14.1 | rs6795735 C/T |
| B3GALTL | 13q12.3 | rs9542236 C/T |