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. Author manuscript; available in PMC: 2014 Nov 30.
Published in final edited form as: J Immunol. 2014 Aug 25;193(7):3388–3397. doi: 10.4049/jimmunol.1400207

FIGURE 1.

FIGURE 1

Infusion of iTregs markedly suppressed the engraftment of donor cells in model one of acute GVHD. Acute (B6-to-F1) GVHD was induced as described in Material and Methods. After two weeks, mice were sacrificed and donor and host splenic lymphocyte subsets were analyzed by flow cytometry. Splenocytes were stained with H2-Kd and H2-Kb to separate the donor cells from host cells. (A) Representative plots for donor and host cells after 14 days. Relative engraftment (B) and absolute numbers (C) of donor cells are shown for each group. Data are shown as mean ± SEM from 5 independent experiments. Each group in one individual experiment includes 3–4 mice (total n=15–20). *** p <0.001.