Table 3.
Risk-adjusted incremental cost associated with postoperative complications stratified by occurrence of acute kidney injury.
| Patients with no acute kidney injury (n=30670) | Patients with acute kidney injury (n=19644) | |||||
|---|---|---|---|---|---|---|
| Risk-adjusted Relative Cost Ratio (95% CI) | Risk-Adjusted Incremental Cost ($1000) Mean (95% CI) | Risk-Adjusted Average Cost ($1000) Mean (95% CI) | Risk-adjusted Relative Cost Ratio (95% CI) | Risk-Adjusted Incremental Cost ($1000) Mean (95% CI) | Risk-Adjusted Average Cost ($1000) Mean (95% CI) | |
| Patients with no other complications | 1 (Reference) | 0 (Reference) | 14.6 (14.5, 14.8) | 1 (Reference) | 0 (Reference) | 26.1 (25.3, 26.8)a |
| Pulmonary complications and/or mechanical ventilation | 1.74 (1.70, 1.77) | 11.0 (10.5, 11.5) | 27.4 (27.0, 27.8) | 1.91 (1.87,1.95)a | 36.2 (35.0, 37.3)a | 76.1 (75.2, 77.0)a |
| Cardiovascular complications and/or need for vasopressors | 1.33 (1.30, 1.37) | 5.2 (4.7, 5.6) | 23.3 (22.9, 23.7) | 1.56 (1.53, 1.60)a | 27.5 (26.2, 28.9)a | 76.4 (75.4, 77.5) a |
| Procedural complications | 1.24 (1.20, 1.28) | 3.4 (2.9, 4.0) | 21.5 (20.9, 22.0) | 1.25 (1.22, 1.29) | 15.5 (13.6, 17.5)a | 77.2 (75.3, 79.0)a |
| Neurological complications and/or delirium | 1.26 (1.22, 1.31) | 3.8 (3.2, 4.4) | 21.4 (20.8, 22.0) | 1.19 (1.16, 1.23)a | 12.1 (10.1, 14.0)a | 74.3 (72.5, 76.2)a |
| Mechanical wound complications and surgical infections | 1.14 (1.09, 1.19) | 1.9 (1.2, 2.6) | 20.3 (19.6, 21.0) | 1.42 (1.37, 1.47)a | 25.7 (22.8, 28.5)a | 87.1 (84.3, 89.9)a |
| Severe sepsis | 1.64 (1.15, 2.33) | 8.8 (0.8, 16.7) | 29.0 (25.3, 32.7) | 1.86 (1.81, 1.92) | 47.7 (44.9, 50.6)a | 103.2 (100.5, 105.9)a |
| Gastrointestinal complications | 1.30 (1.24, 1.36) | 4.1 (3.3, 4.9) | 22.0 (21.1, 22.9) | 1.22 (1.17, 1.27)a | 13.7 (10.6, 16.8)a | 77.2 (74.1, 80.2)a |
| Venous thromboembolism | 1.49 (1.38, 1.60) | 6.7 (5.2, 8.2) | 25.3 (23.8, 26.8) | 1.45 (1.40, 1.51) | 28.0 (24.7, 31.3)a | 89.7 (86.5, 92.9)a |
Abbreviations. CI, confidence interval.
The risk-adjusted relative cost ratios were derived using generalized linear models adjusted for age, gender, ethnicity, primary payer, Charlson Comorbidity Index, surgery type, emergent surgery status, weekend admission, estimated GFR (glomerular filtration rate), and all postoperative complications.
a
P<0.05 using t-test to compare to no acute kidney injury group.