TABLE 1.

Characteristics of permanent section studies

Study	Year	Country	Carcinoma type	BCS	Age range (y)	n	Reexcision ratea	LOE	Study type
Arora et al.24	2007	USA	ADH, DCIS	Lumpectomy	42–87	44	55.0 % (24)	1	Retrospective cohort
Aziz et al.5	2006	Canada	IC, DCIS	Lumpectomy	55b	1,172	13.0 % (152)	1	Retrospective cohort
Cabioglu et al.14	2007	USA	IC, DCIS	Wide local excision, segmental mastectom	27–95	261	44.0% (116)	1	Retrospective cohort
Camp et al.15 (personal communication)	2005	USA	IC, DCIS	Lumpectomy	26–78	78	33.3 % (26)	1	Retrospective cohort
Huston et al.25	2006	USA	DCIS, LCIS, IDC, ILC	Lumpectomy	30–91	171	29.2 % (50)	2	Retrospective cohort
Landercasper et al.26	2010	USA	Breast cancer	Lumpectomy	–	568	19.0 % (108)	1	Retrospective cohort hospital report
Loibl et al.16	2006	Germany	ILC, IDC	Lumpectomy	26–78	248	27.0 % (67)	1	Retrospective cohort RCT–GEPARDUO
McCahill et al.27	2010	USA	DCIS, IDC, ILC	Partial mastectom	–	712	13.0 % (95)	2	Retrospective cohort
Menes et al.28	2005	USA	DCIS, ILC, IDC	Lumpectomy	27–87	459	49.9 % (229)	1	Retrospective cohort Prospective database
Miller et al.29	2004	USA	DCIS, ILC, IDC	BCS	38–64	143	18.2 % (26)	1	Retrospective cohort
Moorthy et al.30	2004	UK	IDC, ILC	Lumpectomy, wide local excision, quadrantectomy	47–73	505	27.1 % (137)	1	Prospective cohort
Mullenix et al.31	2004	USA	IDC, ILC	BCS	48–73	150	51.0 % (90)	1	Retrospective cohort, prospective database
Ooi et al.32	2003	Australia	DCIS, ILC, IDC, IC, medullary	BCS	28–80	742	3.9 % (29)	2	Retrospective cohort
O’Sullivan et al.33	2007	USA	IDC, DCIS, ILC	Lumpectomy	20–91	2,770	59.6 % (1,651)	1	Retrospective cohort, prospective database
Perez34	2003	USA	ILC, IDC	Quadrantectomy, wide local excision, local excision	–	1,347	52.3 % (704)	1	Retrospective cohort
Ramanah et al.35	2008	France	ILC, IDC	Lumpectomy, wide local excision	44–68	206	41.0 % (84)	1	Retrospective cohort
Sanchez et al.36	2010	USA	IDC, ILC, DCIS, atypia	BCS	22–88	351	34.0% (118)	2	Retrospective cohort
van den Broek et al.37	2007	Netherlands	ILC	BCS	–	416	14.4 % (60)	2	Retrospective cohort
Vicini et al.38	2001	USA	DCIS	Excisional biopsy	–	146	64.0 % (95)	2	Retrospective cohort
Results						351b	35 % (±3 %)c

BCS breast conservation surgery, LOE level of evidence (SORT), ADH atypical ductal hyperplasia, IC invasive carcinoma, DCIS ductal carcinoma-in-situ, LCIS lobular carcinoma-in-situ, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma

^aAfter first BCS

^bSample median

^cPooled estimates