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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: Toxicon. 2014 Sep 28;0:36–41. doi: 10.1016/j.toxicon.2014.09.006

Figure 3. Mucosal protection and therapeutic potential of the tripartite cocktail against ricin toxin.

Figure 3

(A-B). Capacity of cPB10 to protect against intranasal ricin challenge. The tripartite cocktail was administered to mice (n=8 mice per group) by intraperitoneal (i.p.) injection 24 h prior to intranasal 10 x LD50 ricin challenge. Mice were monitored for survival (panel A) and morbidity (panel B), as determined by blood glucose levels (Sully et al., 2014); (C) Groups of BALB/c mice (n=8 per group) were challenged with 10 x LD50 ricin and then administered (by i.p. injection) the tripartite cocktail (25 μg of cPB10/mouse) at indicated times (hours). Survival was monitored for five days.