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Treatment with Plk1 inhibitor BI 2536 phenocopies polo mutant phenotype in neuroblast mitoses. (a) Control (DMSO-treated) third instar larval neuroblasts show normal localization of the CPC, whereas BI 2536-treated ones (b) show CPC mislocalization phenotypes similar to those observed in polo mutants. Green, α-tubulin; red, INCENP; blue, DNA; scale bars, 5 µm.
