Table 1.

Rodent model to study acute and chronic pancreatitis

Acute pancreatitis

Cerulein ± lipopolysaccharide (LPS) or ethanol

Bile salt duct infusion

Duct obstruction ± secretagogues

Diet [choline-deficinet ethionine-supplemented (CDE)]

Cytokines

Coxsackie virus group B (CVB)

Chronic pancreatitis

Cerulein (repeated dosing)

Alcohol

Duct infusion such as trinitrobenzene sulfonic acid or sodium taurocholate or dibutyltin dichloride

Duct obstruction

Genetic; Cox-2, CFTR, IKK2, LXRb, PERK, TGF-β1

Immunologic

Diet (CDE)

CVB