Table 2.
Treatment outcome in the intent-to-treat sample using last-observation-carried-forward
| All (n = 88) |
Placebo group (n = 29) |
Medication group (n = 39) |
Support care group (n = 20) |
Statistical tests |
||
|---|---|---|---|---|---|---|
| F (d.f.) | χ2 (d.f.) | |||||
| Time in study, weeks: mean (s.d.) | 7.42 (3.08) | 8.31 (2.16) | 7.64 (2.71) | 5.70 (4.16) | 4.83* (2) | |
| Week 8 HRSD, mean (s.d.) | 14.36 (7.94) | 13.48 (8.68) | 12.41 (7.36) | 19.45 (5.76) | 6.01** (2) | |
| Change in HRSD from baseline to week 8, mean (s.d.) | –7.27 (7.56) | –7.59 (7.98) | –10.05 (6.60) | –1.37 (5.27) | 10.13** (2) | |
| % change HRSD from baseline to week 8, mean (s.d.) | –0.34 (0.36) | –0.36 (0.39) | –0.46 (0.31) | –0.05 (0.27) | 9.62** (2) | |
| Responded, n | 29 | 11 | 17 | 1 | 9.53** (2) | |
| Remitted, n | 18 | 9 | 9 | 0 | 7.30* (2) | |
HRSD, 17-item Hamilton Rating Scale for Depression.
*
P<0.05
**
P<0.01.