Table 6.
Comparison of the most common botulinum toxin formulations
OnabotulinumtoxinA (Botox™) | AbobotulinumtoxinA (Dysport™) | IncobotulinumtoxinA (Xeomin™) | RimabotulinumtoxinB (Myobloc™) | |
---|---|---|---|---|
FDA-approved indications for dystonia | blepharospasm, cervical dystonia | cervical dystonia | blepharospasm, cervical dystonia | cervical dystonia |
Preparation | vacuum dried | freeze dried | powder | liquid |
Available dose sizes (units) | 100, 200 | 300, 500 | 50, 100 | 1000, 2500, 5000 |
Storage | refrigerate | refrigerate | room temperature | refrigerate |
Approximate dose equivalency* | 1 | 2.5 – 3 | 1 | 40 |
As the first FDA-approved BoNT, onabotulinumtoxinA was arbitrarily defined as having a strength of 1. The relative strengths of the others are compared against this value.