Figure 1.

Subconjunctival injection of GW501516, a PPARδ agonist, delayed reepithelialization during corneal wound healing in rats, which could be reversed by GSK3787, a PPARδ antagonist. (a) Representative photographs of rats' ocular surfaces during the evaluation of corneal epithelial wound healing. Green areas represent fluorescein-stained areas of corneal epithelial defects. (b) The percentage rates of the remaining corneal epithelial defect area (% of each initial defect area) are shown at 24 and 48 h after surgery. The ranges of the y-axis differ in each graph. Data are presented as the mean ± SD (n = 7), and significant differences were statistically assessed by ANOVA. ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001 versus GW501516 group.