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. 2014 Nov 16;2014:528783. doi: 10.1155/2014/528783

Table 1.

Underlying causes of portal hypertension in the included studies [1021].

1st author and year N ALD HBV or HCV Cryptogenic ALD + HCV Miscellaneous
Krowka 1999 14 1 1 3 3 1 HCC + HCV, 1 sarcoidosis,
2 PBC, 1 Budd Chiari, 1 AIH
Hoeper 2005 11 7 1 0 2 1 biliary atresia
Reichenberger 2006 14 7 3 3 PBC, 1 Budd Chiari
Sussman 2006 8 4 1 2 1
Fix 2007 35 7 9 3 10 1 HIV, 2 HCC, 2 PBC, 1 AIH
Hoeper 2007 (bosentan) 18 11 3 1 0 1 PVT, 2 AIH
Hoeper 2007 (iloprost) 13 6 2 0 0 1 biliary duct atresia, 4 AIH
Gough and White 2009 11 4 2 0 4 1 ALD + NASH
Hemnes 2009 13 1 8 0 0 1 PBC
Melgosa 2010 13 2 7 0 0 1 hemochromatosis, 2 PBC, 1 portal vein thrombosis
Halank 2011 13 8 1 3 0 1 PBC
Hollatz 2012 11 5 1 0 3 1 ALD + NASH + PBC, 1 biliary atresia
Savale 2013 34 20 4 3 6 PVT, 1 AIH

Total 83 (40%) 43 (20%) 12 (5%) 26 (12%) 41 (20%)

ALD: alcoholic liver disease; HBV: hepatitis B; HCV: hepatitis C; HCC: hepatocellular cancer; PBC: primary biliary cirrhosis; AIH: autoimmune hepatitis; HIV: human immunodeficiency virus; PVT: portal vein thrombosis; NASH: nonalcoholic steatohepatitis.