Table 2.
Predictors of unsuccessful tuberculosis treatment outcomes among 233 rural TB/HIV patients in Ebonyi State, Nigeria, 2011-2012.
| Characteristics | Successful outcome n (%) |
Unsuccessful outcome n (%) |
Crude OR (95% CI) |
Adjusted OR (95% CI) |
Adjusted P value |
|---|---|---|---|---|---|
| Age (years) | |||||
| ≤40 | 106 (60.6) | 69 (39.4) | 1.07 (0.6–2.0) | 1.06 (0.5–2.1) | 0.86 |
| >40 | 36 (62.1) | 22 (37.9) | 1 | 1 | |
| Gender | |||||
| Female | 65 (58.0) | 47 (42.0) | 1.26 (0.8–2.1) | 1.26 (0.7–2.3) | 0.43 |
| Male | 77 (63.6) | 44 (36.8) | 1 | 1 | |
| Facility | |||||
| Public | 23 (38.3) | 37 (61.7) | 3.6 (1.9–6.5) | 3.8 (1.9–7.7) | <0.001 |
| Private | 119 (68.8) | 54 (31.2) | 1 | 1 | |
| Treatment category | |||||
| New | 132 (60.8) | 85 (39.2) | 1.07 (0.4–3.1) | 1.06 (0.4–3.2) | 0.92 |
| Previously treated | 10 (62.5) | 6 (37.5) | 1 | 1 | |
| Type of TB | |||||
| Pulmonary | 139 (61.8) | 86 (38.2) | 1 | 1 | |
| Extrapulmonary | 3 (37.5) | 5 (62.5) | 2.7 (0.6–11.6) | 1.2 (0.3–6.0) | 0.80 |
| Anti-TB regimen | |||||
| Regimen 1 | 72 (55.8) | 57 (44.2) | 1.6 (0.9–2.8) | 1.7 (0.9–3.2) | 0.096 |
| Regimen 2 | 70 (67.3) | 34 (32.7) | 1 | 1 | |
| Received ART | |||||
| Yes | 47 (58.8) | 33 (41.2) | 1.2 (0.7–2.0) | 1.2 (0.5–2.5) | 0.71 |
| No | 95 (62.1) | 58 (37.9) | 1 | 1 | |
| Received CPT | |||||
| Yes | 79 (60.3) | 52 (39.7) | 1.06 (0.6–1.8) | 1.0 (0.5–2.0) | 0.98 |
| No | 63 (61.8) | 39 (38.2) | 1 | 1 |
Regimen 1: 2RHZE/6EH; regimen 2: 2RHZE/4RH (R: rifampicin, H: isoniazid, Z: pyrazinamide, and E: ethambutol); OR: odds ratio; ART: antiretroviral therapy; TB: tuberculosis; HIV: human immunodeficiency virus; CPT: cotrimoxazole preventive therapy.