Table 2.

Comparison between M. tuberculosis and M. smegmatis for nutrient utilization

Carbon source	Mtb	Msm	Carbon source	Mtb	Msm
2-oxoglutarate	✓	NA	Oxalomalate	✓	NA
Acetate	✓	✓	Propanoate	X	✓
Acetoacetic acid	✓	NA	Pyruvate	✓	✓
Adenosine	X	X	D-serine	✓	X
D-alanine	✓	✓	D-tagatose	X	NA
L-alanine	✓	✓	D-trehalose	✓	✓
L-asparagine	✓	✓	Tween 20	✓	✓
Butyrate	✓	✓	Tween 40	✓	✓
Caproic acid	✓	✓	Tween 80	✓	✓
Citrate	✓	✓
D-fructose-6-phosphate	✓	✓	Nitrogen source
D-glucose-6-phosphate	✓	✓	L-Alanine	✓	✓
D-glucose	✓	✓	Allantoin	X	✓
L-glutamate	✓	✓	L-Asparagine	✓	✓
L-glutamine	✓	✓	L-Aspartic acid	X	✓
Glycerol	✓	✓	L-Cysteine	✓	✓
Glycine	✓	NA	D-Galactosamine	✓	✓
L-lactate	✓	✓	D-Glucosamine	X	✓
D-malate	X	✓	L-Glutamic acid	✓	✓
L-malate	✓	✓	L-Glutamine	✓	✓
D-mannose	X	✓	L-Ornithine	✓	✓
Methyl-pyruvate	✓	✓	D-Serine	✓	✓
Mono methyl-succinate	✓	✓	L-Serine	✓	✓
N-acetyl-glucosamine	X	✓	L-Threonine	X	✓

The nutrient sources in bold indicate the differential utilization by Msm and Mtb. (✓=growth, X=no growth, NA=not available).