Table 3.

Sensitivity and specificity and AUC of 5 identified miRNAs in detecting early-stage NSCLC

MiRNA	Training set (NSCLC vs. Healthy)			Validation set (NSCLC vs. Control)
	Sensitivity (95% CI)	Specificity (95% CI)	AUC (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	AUC (95% CI)
miR-20a	0.84 [0.76-0.90]	0.83 [0.71-0.92]	0.91 [0.86-0.95]	0.83 [0.74-0.89]	0.81 [0.72-0.88]	0.89 [0.85-0.93]
miR-223	0.87 [0.80-0.93]	0.86 [0.75-0.94]	0.96 [0.94-0.98]	0.87 [0.80-0.92]	0.86 [0.78-0.92]	0.94 [0.91-0.96]
miR-21	0.70 [0.61-0.78]	0.68 [0.55-0.80]	0.79 [0.73-0.86]	0.67 [0.54-0.72]	0.68 [0.59-0.77]	0.77 [0.71-0.83]
miR-155	0.87 [0.80-0.93]	0.87 [0.75-0.94]	0.94 [0.91-0.97]	0.86 [0.78-0.91]	0.84 [0.76-0.91]	0.92 [0.89-0.96]
miR-145	0.73 [0.64-0.81]	0.75 [0.62-0.85]	0.82 [0.75-0.88]	0.70 [0.61-0.78]	0.68 [0.58-0.76]	0.77 [0.71-0.83]