FIG 4.

Reverse cumulative distribution of ELISA antibody titers against OspA serotypes 1 to 6 (marked by different color bars and labeled by number) in seronegative and seropositive participants receiving three priming immunizations with the 60-μg dose and a booster at 9 to 12 months after the first immunization. The seronegative participants are represented by solid lines, and the seropositive participants are represented by dashed lines. The data are at baseline (red lines), 28 days after the third priming immunization (blue lines), before the 9- to 12-month booster (green lines), and 28 days after the 9- to 12-month booster (purple lines).