TABLE 1.
Protection against B. canis in mice immunized with Omp31 by using different strategies of immunization
| Vaccine (n = 5) | Adjuvant | Log10 B. canis in the spleena | Log unit of protection |
|---|---|---|---|
| PBS | 6.18 ± 0.11 | ||
| rOmp31 | Quil A | 4.14 ± 0.68 | 1.86b |
| Montanide | 4.63 ± 0.50 | 1.42b | |
| IFA | 4.37 ± 0.36 | 1.66b | |
| HA | 4.37 ± 0.82 | 1.65b | |
| pCIOmp31 | 5.67 ± 0.66 | 0.66 | |
| pCIOmp31+boost | IFA | 4.53 ± 0.92 | 1.50b |
| HKBC | IFA | 2.25 ± 0.58 | 3.48c |
a
The content of bacteria in spleens is represented as the mean log CFU ± SD per group.
b
Significantly different (P < 0.05) from the value for PBS-immunized mice by Dunnett's t test.
c
Significantly different (P < 0.01) from the value for PBS-immunized mice by Dunnett's t test.