FIG 7.

mfsR/mfsABC synteny comparisons. (A) mfsR and mfsABC on ICEclc, where they are separated by 12.7 kb. Details of the promoter regions are illustrated within boxes. Gray shaded boxes point to regions of 70% nucleotide identity between the mfsR and mfsA promoters. (B) mfsR and mfsABC homologs in Acidovorax sp. strain JS42 (ajs_2925). Note that the annotated mfsR in JS42 is longer than its ICEclc counterpart and overlaps with the predicted OP1 box (see details in Fig. S4 in the supplemental material). A transposase of the IS116/IS10/IS902 family has disrupted the sequence of mfsB, and another transposase (of the IS4 family) is located downstream of mfsR. (C) mfsR and mfsABC in A. hydrophila SSU (HMPREF1171_02726). Sequences highlight the similarity between the OP boxes in the different systems (for further details, see Fig. S4).