TABLE 2.

BTV-8 neutralizing antibody response in vaccinated and control sheep

Group	Animal	BTV-8 neutralizing antibody titera at:
		Day −21	Day 0	Day 14
G1 (unvaccinated control)	10349	<0.48	<0.48	0.89
	10372	<0.48	<0.48	1.12
	10375	<0.48	<0.48	2.08
	10412	<0.48	<0.48	1.28
	10434	<0.48	<0.48	n.a.
	20133	<0.48	<0.48	1.20
	Mean ± SD	<0.48	<0.48	1.31 ± 0.45
G2 (B1BTV-8VP2/VP5)	10358	<0.48	0.53	2.08
	10376	<0.48	0.80	2.08
	10379	<0.48	0.72	1.76
	10414	<0.48	1.20	1.20
	20152	<0.48	0.72	1.76
	Mean ± SD	<0.48	0.79 ± 0.25	1.78 ± 0.36
G3 (B1BTV-8VP2)	10348	<0.48	0.72	1.68
	10360	<0.48	0.80	1.85
	10371	<0.48	<0.48	1.76
	10374	<0.48	<0.48	2.16
	10424	<0.48	0.53	1.76
	Mean ± SD	<0.48	<0.60 ± 0.15	1.84 ± 0.19
G4 (B1BTV-88VP2, low dose)	10356	<0.48	<0.48	1.77
	10363	<0.48	<0.48	2.64
	10385	<0.48	0.72	1.20
	10420	<0.48	<0.48	1.37
	20103	<0.48	<0.48	1.76
	Mean ± SD	<0.48	<0.53 ± 0.11	1.75 ± 0.56

^aThe neutralizing titer in each sheep was expressed as log₁₀ of the 50% protective dose (PD₅₀).