FIG 7.

Frequency of SVV-specific CD4 T and CD8 T cells following acute infection in PBMC. The frequencies (means ± SEM) of SVV-specific CD4 (white bar) and CD8 (gray bar) T cells in PBMC samples producing IFN-γ (A and B), TNF-α (C and D), MIP-β (E and F), and IL-2 (G and H) were measured by intracellular cytokine staining following stimulation with SVV lysate (A, C, E, G) or an SVV overlapping peptide pool (B, D, F, H) (ORFs 4, 9, 11, 16, and 31) (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001 for CD4) (++, P < 0.01; +++, P < 0.001; ++++, P < 0.0001 for CD8).