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. 2014 Dec;88(23):13523–13546. doi: 10.1128/JVI.01673-14

FIG 6.

FIG 6

EEHV1A-1B chimeric domain III patterns and boundaries relative to EEHV2. The diagrams show SimPlot comparisons of the nucleotide identity patterns between EEHV1A, EEHV1B, and EEHV2 across both sides of EEHV1B chimeric domain CD-III (8.3-kb) encompassing ORF-M–ORF-N(vCXCL1)–UDG–gL–ORF-O–ORF-P–ORF-Q. (a) CD-III left-hand side (LHS) from U77(HEL, C-term) to U82.5(ORF-O, C-term). A 4,330-bp segment of EEHV1A(Kala, NAP18), is compared with EEHV1B(Kiba, NAP14) (red) and EEHV2(Kijana, NAP12) (gray), map coordinates 143,625 to 147,955. (b) CD-III left-hand side from U77(HEL, C-term) to U82.5(ORF-O, C-term). A 4,330-bp segment of EEHV1A(Kala, NAP18) is compared with EEHV1B(Haji, NAP19) (green) and with EEHV2(Kijana, NAP12) (gray), map coordinates 143,625 to 147,955. (c) CD-III right-hand side (RHS) from U82.5(ORF-O, C-term) to U85.5(ORF-K, N-term). A 4,750-bp segment of EEHV1A(Kumari, NAP11), is compared with a matching 4,200-bp segment of EEHV1B(Kiba, NAP14) (red) and a 4,650-bp segment of EEHV2(Kijana, NAP12) (gray), map coordinates 143,401 to 153,115. (d) CD-III right-hand side from U83.5(ORF-O, C-term) to U85.5(ORF-K N-term). The same segment of EEHV1A(Kumari) is compared with EEHV1B(Haji, NAP19) (green) and EEHV2(Kijana, NAP12) (gray), map coordinates 148,401 to 153,115. The relevant GenBank file accession numbers are included in Table S1 in the supplemental material.