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. 2014 Dec;88(23):13547–13569. doi: 10.1128/JVI.01675-14

TABLE 2.

Summary of PCR-sequenced EEHV3, EEHV4, EEHV5A, EEHV5B, and EEHV6 gene coding regions

Gene/ORF no./IDa HCMV ORF HSV ORF Orientationb Protein name Statusc Presence/absence of the indicated ORFd
EEHV3 NAP27 EEHV4 NAP22 EEHV5A NAP28 EEHV5A NAP50 EEHV5B NAP58 EEHV6 NAP35
U39 UL55 UL29 F gB Core + + + + +
U38 UL54 UL30 F POL Core + + + + + +
U33 UL49 Nil F Cys-rich β/γ + + + +
U28 UL45 UL39 F RRA Core + + + +
U27.5/ORF-H Nil UL40 F RRB α/β2 + + + +
U27/ORF-I UL44 UL42 F PPF Core + + +
U45.7/ORF-J Nil Nil F Novel +
U46 UL73 UL49A F gN Core +
U47/ORF-D UL74 Nil R gO β +
U48 UL75 UL22 R gH Core + + + +
U48.5/ORF-E Nil UL23 R TK α/γ + + + +
U49 UL76 UL24 F Core + + + +
U50 UL77 UL25 F PAC2 Core + + +
U51 UL78 Nil F vGPCR1 β + + + +
U57 UL86 UL19 R MCP Core + + + +
U60ex3 UL89 UL15ex2 R TERex3 Core + + + + +
U62 UL91 Nil F β/γ + + +
U63 UL92 Nil F β/γ +
U66ex2 Nil Nil R TERex2 Core +
U66ex1 UL89ex1 UL15ex1 R TERex1 Core +
U70 UL98 UL12 F EXO Core + + + + + +
U71 UL99 UL11 F myrTeg. Core + + + + + +
U72 UL100 UL10 R gM Core + + + + + +
U73/ORF-G Nil UL09 F OBP α/β + + + + + +
U76 UL104 UL06 R POR Core + + + + + +
U77 UL105 UL05 F HEL Core + + + + + +
U77.5/ORF-M Nil Nil F Nuclear Novel + + +
U80.5/ORF-N Nil Nil R vCXCL1 Novel + + +
U81 UL114 UL02 R UDG Core + + +
U82 UL115 UL01 R gL Core + + +
U82.5/ORF-Oex3 Nil Nil R S/TGlyP Novel + + +
U82.5/ORF-Oex2 Nil Nil R S/TGlyP Novel + + +
U82.5/ORF-Oex1 Nil Nil R S/TGlyP Novel + + +
U83.5/ORF-Pex2 Nil Nil R S/TGlyP Novel +
U83.5/ORF-Pex1 Nil Nil R S/TGlyP Novel +
U84.5/ORF-Q Nil Nil R S/TGlyP Novel A
U85.5/ORF-Kex3 Nil Nil R SplGlyP Novel + + +
U85.5/ORF-Kex2 Nil Nil R SplGlyP Novel + + +
U85.5/ORF-Kex1 Nil Nil R SplGlyP Novel + + +
U86.5/ORF-L Nil Nil R IE-like Novel + + +
a

ID, identification.

b

F, forward; R, reverse.

c

Novel, not found in any other herpesviruses; β, betaherpesvirus subfamily only; Core, common to all herpesvirus subfamilies; β/γ, betaherpesvirus and gammaherpesvirus subfamilies only; α/β, alphaherpesvirus and betaherpesvirus subfamilies only; α/β2, alphaherpesvirus subfamily and roseoloviruses only.

d

+, partial or intact ORF present (see Table S1 in supplemental material for detailed coordinates, percent divergence, and GenBank accession numbers); A, gene absent.