TABLE 2.
Gene/ORF no./IDa | HCMV ORF | HSV ORF | Orientationb | Protein name | Statusc | Presence/absence of the indicated ORFd |
|||||
---|---|---|---|---|---|---|---|---|---|---|---|
EEHV3 NAP27 | EEHV4 NAP22 | EEHV5A NAP28 | EEHV5A NAP50 | EEHV5B NAP58 | EEHV6 NAP35 | ||||||
U39 | UL55 | UL29 | F | gB | Core | + | + | + | + | + | |
U38 | UL54 | UL30 | F | POL | Core | + | + | + | + | + | + |
U33 | UL49 | Nil | F | Cys-rich | β/γ | + | + | + | + | ||
U28 | UL45 | UL39 | F | RRA | Core | + | + | + | + | ||
U27.5/ORF-H | Nil | UL40 | F | RRB | α/β2 | + | + | + | + | ||
U27/ORF-I | UL44 | UL42 | F | PPF | Core | + | + | + | |||
U45.7/ORF-J | Nil | Nil | F | Novel | + | ||||||
U46 | UL73 | UL49A | F | gN | Core | + | |||||
U47/ORF-D | UL74 | Nil | R | gO | β | + | |||||
U48 | UL75 | UL22 | R | gH | Core | + | + | + | + | ||
U48.5/ORF-E | Nil | UL23 | R | TK | α/γ | + | + | + | + | ||
U49 | UL76 | UL24 | F | Core | + | + | + | + | |||
U50 | UL77 | UL25 | F | PAC2 | Core | + | + | + | |||
U51 | UL78 | Nil | F | vGPCR1 | β | + | + | + | + | ||
U57 | UL86 | UL19 | R | MCP | Core | + | + | + | + | ||
U60ex3 | UL89 | UL15ex2 | R | TERex3 | Core | + | + | + | + | + | |
U62 | UL91 | Nil | F | β/γ | + | + | + | ||||
U63 | UL92 | Nil | F | β/γ | + | ||||||
U66ex2 | Nil | Nil | R | TERex2 | Core | + | |||||
U66ex1 | UL89ex1 | UL15ex1 | R | TERex1 | Core | + | |||||
U70 | UL98 | UL12 | F | EXO | Core | + | + | + | + | + | + |
U71 | UL99 | UL11 | F | myrTeg. | Core | + | + | + | + | + | + |
U72 | UL100 | UL10 | R | gM | Core | + | + | + | + | + | + |
U73/ORF-G | Nil | UL09 | F | OBP | α/β | + | + | + | + | + | + |
U76 | UL104 | UL06 | R | POR | Core | + | + | + | + | + | + |
U77 | UL105 | UL05 | F | HEL | Core | + | + | + | + | + | + |
U77.5/ORF-M | Nil | Nil | F | Nuclear | Novel | + | + | + | |||
U80.5/ORF-N | Nil | Nil | R | vCXCL1 | Novel | + | + | + | |||
U81 | UL114 | UL02 | R | UDG | Core | + | + | + | |||
U82 | UL115 | UL01 | R | gL | Core | + | + | + | |||
U82.5/ORF-Oex3 | Nil | Nil | R | S/TGlyP | Novel | + | + | + | |||
U82.5/ORF-Oex2 | Nil | Nil | R | S/TGlyP | Novel | + | + | + | |||
U82.5/ORF-Oex1 | Nil | Nil | R | S/TGlyP | Novel | + | + | + | |||
U83.5/ORF-Pex2 | Nil | Nil | R | S/TGlyP | Novel | + | |||||
U83.5/ORF-Pex1 | Nil | Nil | R | S/TGlyP | Novel | + | |||||
U84.5/ORF-Q | Nil | Nil | R | S/TGlyP | Novel | A | |||||
U85.5/ORF-Kex3 | Nil | Nil | R | SplGlyP | Novel | + | + | + | |||
U85.5/ORF-Kex2 | Nil | Nil | R | SplGlyP | Novel | + | + | + | |||
U85.5/ORF-Kex1 | Nil | Nil | R | SplGlyP | Novel | + | + | + | |||
U86.5/ORF-L | Nil | Nil | R | IE-like | Novel | + | + | + |
ID, identification.
F, forward; R, reverse.
Novel, not found in any other herpesviruses; β, betaherpesvirus subfamily only; Core, common to all herpesvirus subfamilies; β/γ, betaherpesvirus and gammaherpesvirus subfamilies only; α/β, alphaherpesvirus and betaherpesvirus subfamilies only; α/β2, alphaherpesvirus subfamily and roseoloviruses only.
+, partial or intact ORF present (see Table S1 in supplemental material for detailed coordinates, percent divergence, and GenBank accession numbers); A, gene absent.