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. 2014 Nov;80(22):6976–6991. doi: 10.1128/AEM.01576-14

FIG 6.

FIG 6

Tolerance of persister cells to tobramycin and tetracycline in the presence of cis-DA. Persister cell subpopulations of P. aeruginosa planktonic populations were exposed to tobramycin (A) and tetracycline (B) in the presence and absence of cis-DA (100 nM) for a period of 24 h. Shown are data for treatments with saline, cis-DA in saline, antimicrobial in saline, and antimicrobial and cis-DA in saline. Tetracycline was used at a concentration of 100 μg/ml, and tobramycin was used at a concentration of 20 μg/ml. Viability was determined throughout the experiment. The averages of data from 3 experiments are shown. Error bars indicate standard deviations (*, P < 0.01 [significantly different from persister cells treated with saline, cis-DA, and antimicrobials, as indicated by one-way ANOVA]).