TABLE 2.
Most divergent Melbournevirus ORFs
| Melbournevirus ORF (protein size [aa]) | % identical residuesa |
Predicted function and comment | ||
|---|---|---|---|---|
| Cannes 8 virus | Marseillevirus | Lausannevirus | ||
| 025 (384) | 71 | 99 | 76 | 6 paralogous remnants in Melbournevirus |
| 027 (181) | Absent | Absent | Absent | >40 paralogous remnants in Cannes 8 virus |
| 033 (118) | 99 | 38 | 30 | |
| 034 (495) | 39 | 27 | Absent | Helicase, 2 remnants in Cannes 8 virus |
| 035 (1,098) | 90; partial | 93; partial | 82 | Helicase, 2 remote paralogs in Melbournevirus |
| 036 (103) | 61; no annot. | 95; no annot. | Absent | 1 paralogs + 1 remnant in Cannes 8 virus |
| 037 (252) | 55 | 99 | 29 | F box containing, 6 paralogs in Cannes 8 virus and Melbournevirus |
| 038 (430) | 66 | 100 | 53 | Restriction endonuclease, 15 paralogs in Cannes 8 virus 10 paralogs in Melbournevirus |
| 054 (166) | 88 | 98 | 47 | |
| 058 (129) | 30; partial | 46; partial | 38; partial | 2 paralogs in Cannes 8 virus, 1 in Marseillevirus |
| 059 (398) | 38 | 38 | 28 | Zinc finger protease, 4 paralogs in Cannes 8 virus, 2 in Melbournevirus |
| 113 (172) | 99 | 26 | 24 | |
| 124 (1,083) | 99; partial | 83; partial | 99 | Helicase |
| 125 (144) | Absent | Absent | Absent | |
| 166 (155) | 99 | 31; partial | 22 | |
| 222 (242) | 91; partial | Absent | Absent | |
| 223 (398) | 50 | 51 | 38 | MutH/HJR-like endonuclease |
| 224 (134) | 88; no annot. | 87; no annot. | Absent | |
| 270 (537) | 89 | 87 | 45 | MutH/HJR family nuclease, 2 paralogs in Cannes 8 virus, 4 in Marseillevirus |
| 286 (458) | 29 | 24 | 25 | Zinc finger protein, 4 paralogs in Cannes 8 virus, 3 in Marseillevirus, 2 in Melbournevirus |
| 287 (124) | 30; partial | 32; partial | 28; partial | |
| 301 (106) | 100; partial | Absent | 67 | |
| 306 (193) | 65 | 55 | 59 | 2 paralogs in Melbournevirus, 1 in Cannes 8 virus |
| 307 (438) | 74 | 58; partial | 39; partial | MutH/HJR-like endonuclease, 1 paralog in Melbournevirus |
| 311 (434) | 59 | 100 | 53 | Restriction endonuclease, 10 paralogs in Melbournevirus and Cannes 8 virus, 8 paralogs in Marseillevirus |
| 312 (183) | 75 | 94; no annot. | 46 | |
| 336 (137) | 97 | 42 | Absent | |
| 345 (537) | 50 | 99 | 47 | HNH homing endonuclease |
| 346 (355) | 43 | 43 | 42 | Restriction endonuclease |
| 364 (504) | 61 | 96 | 53 | Restriction endonuclease |
| 365 (424) | 66 | 66 | 57 | Restriction endonuclease |
| 370 (104) | 100 | 30; partial | 26 | |
a
annot., annotation.