TABLE 5.

Estimation of evolutionary dynamics of BTV at Beatrice Hill Farm, Northern Territory, from Path-O-Gen and Beast analyses^a

BTV segment (protein)	No. of amino acids	No. of sequences	Date range	Correlation coefficient for best-fitting root	Substitution rateb	95% HPDc	TMRCAd (95% HPD)
1 (VP1)	1,302	28	1977–2010	0.7583	4.34E−04	3.47E−4 to 5.17E−4	210 (171–252)
2 (VP2)	961	18	1979–2010	0.9717	3.92E−04	2.91E−4 to 4.91E−4	85 (67–105)
3 (VP3)	901	27	1977–2010	0.3626	4.40E−04	3.24E−4 to 5.50E−4	173 (130–218)
4 (VP4)	644	28	1977–2010	0.3946	4.75E−04	3.25E−4 to 6.19E−4	164 (120–216)
5 (NS1)	552	28	1977–2010	0.4914	4.55E−04	2.62E−4 to 6.44E−4	667 (396–1012)
6 (VP5)	526	18	1979–2010	0.9672	4.77E−04	3.05E−4 to 6.58E−4	63 (47–82)
7 (VP7)	349	24	1977–2010	−0.3642	3.56E−04	1.80E−4 to 5.33E−4	188 (101–295)
8 (NS2)	354	27	1977–2010	0.7811	5.27E−04	3.36E−4 to 7.18E−4	102 (73–137)
9 (VP6)	330	28	1977–2010	−0.0149	4.46E−04	2.48E−4 to 6.42E−4	107 (45–182)
9 (NS4)	77–79	28	1977–2010	0.3635	6.66E−04	2.69E−4 to 1.12E−3	83 (48–131)
10 (NS3)	229	28	1977–2010	0.7742	3.79E−04	2.10E−4 to 5.63E−4	210 (120–319)
10 (NS3a)	216	28	1977–2010	0.7504	4.08E−04	2.24E−4 to 6.06E−4	209 (120–318)

^aData for segments with low correlation coefficients are underlined and in bold italics.

^bNucleotide substitutions per site per year. The model used was SRD06 (31). The following segments were excluded: Seg-3 of BTV 15; Seg-7 of BTV 3, -7, -15, and -16; and Seg-8 of BTV 15.

^cHPD, highest probability density.

^dTMRCA, time to the most recent common ancestor before the most recent date of isolation (in years).