FIG 6.

Effects of kinesin and dynein inhibitors. HSV particles were prepared from the cytoplasm of Vps4A- and Vps4A-EQ-expressing cells, and motility measured in the presence of ATP supplemented with buffer (No inhibitor), 1 mM AMP-PNP, 5 μM sodium orthovanadate, or a mixture of AMP-PNP and sodium orthovanadate. Plotted values represent the means and standard deviations. The numbers of HSV particles examined under each condition for Vps4A and Vps4A-EQ samples, respectively, were as follows: no inhibitor, 1,149 and 942; AMP-PNP, 1,069 and 1,099; sodium orthovanadate, 778 and 954; and AMP-PNP plus sodium orthovanadate, 2,073 and 745.