TABLE 1.
Study | No. of macaques | Vaccine | ART | Challengeb | Outcome of vaccine | Reference |
---|---|---|---|---|---|---|
1 | 11 | Kunjin SIV | No | SIVmac251, intravenously | No effect | 29 |
2 | 31 | Peptide immunotherapy (n = 21) or control (n = 10) | Yesc | SIVmac251, intravenously | Immunotherapy effective | 31 |
3 | 2 | Influenza virus-SIV | No | SIVmac251, intrarectally | No effect | 30 |
A total of 44 macaques were studied.
The same stock of SIVmac251, supplied by R. Pal and N. Miller, was used for all infections.
The animals received ART from weeks 3 to 10 after infection.