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. 2014 Dec;80(24):7496–7504. doi: 10.1128/AEM.02926-14

FIG 5.

FIG 5

Lactobacillus acidophilus ATCC 4356 (L.4356) decreases Niemann-Pick C1-like 1 (NPC1L1) expression in the small intestines of ApoE−/− mice. (A) Real-time PCR of NPC1L1 mRNA in the small intestines of L. acidophilus ATCC 4356-treated mice was compared to that in the small intestines of the controls. The signal obtained from the control mice was set to a normalized value of 100 arbitrary units. β-Actin was used as an internal control. The data are presented as the mean ± SEM. *, P < 0.05 versus controls. (B) Protein expression of NPC1L1 in the small intestines of L. acidophilus ATCC 4356-treated mice was compared to that in the small intestines of the control group. Bar graphs show the relative quantification of NPC1L1 (normalized to β-actin; n = 3). *, P < 0.05 versus controls.