TABLE 4.
Detection of strain-specific alleles in natural infection
Locusa | Region | Mean no. of alleles detected/infection (maximum) | No. of infections/total with: |
|
---|---|---|---|---|
Multiple alleles at locus | >2 alleles at locus | |||
omp5 | Tropical | 2.4 ± 1.0 (4) | 19/23 | 10/23 |
Temperate | 1.3 ± 0.5 (2) | 3/8 | 0/8 | |
omp9 | Tropical | 2.8 ± 1.2 (5) | 19/23 | 13/23 |
Temperate | 1.0 ± 0.0 (1) | 0/4 | 0/4 | |
omp12 | Tropical | 2.7 ± 1.1 (5) | 18/23 | 13/23 |
Temperate | 1.1 ± 0.4 (2) | 1/8 | 0/8 | |
omp13 | Tropical | 2.2 ± 1.0 (4) | 18/23 | 8/23 |
Temperate | 1.1 ± 0.4 (2) | 1/8 | 0/8 | |
omp14 | Tropical | 2.7 ± 1.4 (6) | 17/23 | 12/23 |
Temperate | 1.1 ± 0.4 (2) | 1/8 | 0/8 |
The greater number of alleles per tropical region infection compared to the temperate region infection was statistically significant for all loci collectively at P < 0.0001 and for each locus as follows: omp5, P = 0.006; omp9, P = 0.007; omp12, P = 0.0004; omp13, P = 0.006; and omp14, P = 0.004.