TABLE 2.
Assessment of superinfection by homologous B. burgdorferi in C3H and NOD mice
| Tissue collected (day postchallenge) | No. of samples positive for superinfection froma: |
No. of samples from naïve C3H mice (control) positive for infection with ha wtB31-kanr | ||
|---|---|---|---|---|
| wtB31-gentr- infected C3H mice | wtB31-gentr- infected NOD mice | wtB31-gentr- infected NOD mice treated with SCID mouse-derived sera | ||
| Blood (7) | 0/5b | 7/9 | 1/4 | 5/5 |
| Ear (14) | 0/5 | 0/9 | 0/4 | 5/5 |
| Ear (21) | 0/5 | 0/9 | 0/4 | 5/5 |
| Tissues (28) | ||||
| Ear | 0/5 | 0/9 | 0/4 | 5/5 |
| Heart | 0/5 | 1/9 | 0/4 | 5/5 |
| Bladder | 0/5 | 0/9 | 0/4 | 3/5 |
| Joint | 0/5 | 0/9 | 0/4 | 5/5 |
| Total no. of infected micec (28) | 0/5 | 1/9 | 0/4 | 5/5 |
a
Superinfection was performed via tissue transplantation with the host-adapted (ha) wtB31-kanr clone.
b
Values listed correspond to numbers of cultures positive/numbers tested.
c
Based on combined results obtained from culturing ear, heart, bladder, and tibiotarsal joint.