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Loss of mir-155 impairs nasopharyngeal clearance of S. pneumoniae colonization. WT and mir155KO mice were inoculated intranasally with a known noninvasive colonizing strain of S. pneumoniae (P1121), and the bacterial loads in their nasopharynxes were enumerated. n = 7 to 16 per group per time point. Statistical significance was determined by the Wilcoxon rank sum test. ***, P < 0.001.
