TABLE 1.
Description of C. perfringens strains used in this study
| Strain | Description (disease or source, location, date of isolation) | Origin reference | Toxin genesa | Sialidase genesb |
|---|---|---|---|---|
| Type A | ||||
| Food poisoning strains | ||||
| NCTC8239 | Food poisoning, Europe, 1950s | 9 | cpe | nanH |
| NCTC10239 | cpe | nanH | ||
| SM101 | cpe | nanH | ||
| C1841 | Food poisoning, Vermont, USA, 1980s | 24 | cpe, cpb2h1 | nanJ, nanH |
| FD1041 | Food poisoning, North America, 1980s | cpe | nanH | |
| E13 | Food poisoning, North America, 1990s | cpe | nanH | |
| 527 | cpe | nanH | ||
| 01E803 | Food poisoning, Oklahoma, USA, 1999 | 25 | cpe | nanJ, nanH |
| 01E809 | cpe | nanJ, nanH | ||
| Sporadic and antibiotic-associated diarrhea strains | ||||
| F4969 | Sporadic diarrhea, Europe, 1990s | 9 | cpe | nanJ, nanI, nanH |
| F5603 | cpe, cpb2h1 | nanJ, nanI, nanH | ||
| F4859 | cpe, cpb2h2 | nanJ, nanH | ||
| B40 | Antibiotic-associated diarrhea, Europe, 1980s | 9 | cpe, cpb2 | nanJ, nanI, nanH |
| F38660 | Antibiotic-associated diarrhea, North America, 1990s | 24 | cpe | nanJ, nanI, nanH |
| X5722 | cpe, cpb2h2 | nanJ, nanI, nanH | ||
| W30554 | cpe, cpb2 | nanJ, nanI, nanH | ||
| Strains from healthy people | ||||
| 8–6 | Healthy North Americans, 2000s | 26 | cpe-negative | nanJ, nanI, nanH |
| 168–3 | cpe, cpb2 | nanJ, nanI, nanH | ||
| 180–2 | cpe, cpb2 | nanJ, nanI, nanH | ||
| 042–03-2 | cpe-negative | nanJ, nanI, nanH | ||
| 011–03-6 | cpe, cpb2 | nanJ, nanI, nanH | ||
| Type C | ||||
| Pigbel strains | ||||
| CN5383 | Pig-Bel, Papua New Guinea, 1970s | 15 | cpb, tpeL | nanJ, nanI, nanH |
| CN5388 | cpb, cpe, cpb2 | nanJ, nanI, nanH | ||
| Bar 3 | Pig-Bel, Papua New Guinea, ?c | cpb, tpeL, cpb2 | nanJ, nanI, nanH | |
| Darmbrand enteritis necroticans strains | ||||
| CN2076 | Darmbrand, Hamburg, Germany, 1950s | 16 | cpb, cpe | nanJ, nanH |
| CN3748 | cpb, cpe | nanJ, nanH | ||
| CN3753 | cpb, cpe | nanJ, nanH | ||
| CN3758 | cpb, cpe | nanJ, nanH | ||
| CN3763 | cpb, cpe | nanJ, nanH | ||
a
cpe encodes enterotoxin; cpb2h1 and cpb2h2 encode two beta 2 toxin variants; cpb encodes beta toxin; tpeL encodes the toxin perfringens large (TpeL) toxin.
b
As detected by PCR and Southern blot assays in the current study.
c
?, date unknown or unavailable.