FIG 3.

Localization of B. cenocepacia in a CF lung obtained at autopsy. (A) Section of distal lung parenchyma from a 20-year-old male (patient 1) (Table 1) whose prior sputum culture was positive for B. cenocepacia and negative for P. aeruginosa. Highly inflamed alveoli contain cells and particulate matter that react strongly with Bcc antiserum. (B) Higher-power view from panel A, again illustrating predominantly intracellular material in phagocytes and occasional intercellular individual bacteria or pairs/small clusters of bacteria.